Sid Meier's Civilization: Beyond Earth

https://www.youtube.com/watch?v=qtYWqE55s24  

Sid Meier's Civilization®: Beyond Earth™ is a new science-fiction-themed entry into the award-winning Civilization series. As part of an expedition sent to find a home beyond Earth, lead your people into a new frontier, explore and colonize an alien planet and create a new civilization in space. A New Beginning for Mankind is coming Fall/Autumn 2014.

The Civilization series have always been very cool games and now they are breaking away from the history aspect and throwing the action it to space! With that, it's safe to say the possibilities are limitless.